Informatics Methods for Exposure Health

Presentation Type: Workshop - Instructional
Not recorded for AMIA Now

Presentation Time: 08:00 AM - 10:00 AM

Primary Track: Clinical Research Informatics


A substantial portion of disease and wellbeing can be attributed to and or modulated by exposures. Comprehensive quantification of the effects of the modern environment on health requires considering data from all contributing exposures (exposome) which can span endogenous processes within the body, biological responses of adaptation to environment, physiological manifestations of these responses, and socio-behavioral factors. While overall trends are documented in the literature, there is a great deal of specificity and vis-à-vis temporal and spatial resolution detail that remains to be understood. Generating detailed exposomes requires integration of data from wearable and stationary sensors, environmental monitors, personal activities, physiology, medication use and other clinical data, genomic and other biospecimen-derived, person-reported, and computational models, accommodating multiple and variable spatio-temporal resolutions and accounting for multiple study, experimental and analytical designs.

In this tutorial, we will provide attendees with a comprehensive instructional seminar of the state of the art in exposure health informatics. We will share our learnings from conducting various exposure health studies using Exposure Health Informatics Ecosystem as a generalizable multi-scale and multi-omics ecosystem for future deployment and development of exposure health informatics methods and technologies. We will conclude with an open floor to discuss innovations and collaborations in exposure health informatics research.

Speaker(s):
Ram Gouripeddi, MD
University of Utah

Fatemeh Shah-Mohammadi, PhD
University of Utah

Mollie Cummins, PhD, RN, FAAN, FACMI
University of Utah

Katherine Sward, PhD
University of Utah

Julio Facelli, PhD
University of Utah

Author(s):
Ram Gouripeddi, MD - University of Utah; Fatemeh Shah-Mohammadi, PhD - University of Utah; Mollie Cummins, PhD, RN, FAAN, FACMI - University of Utah; Katherine Sward, PhD - University of Utah; Julio Facelli, PhD - University of Utah;

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