Weight and blood-based markers of cachexia predict disability, hospitalization and worse survival in cancer immunotherapy patients

Poster Number: P109
Presentation Time: 05:00 PM - 06:30 PM

Abstract Keywords: Biomarkers, Cancer Prevention, Real-World Evidence Generation
Primary Track: Applications
Programmatic Theme: Clinical Research Informatics

This study examined the association between several routinely collected cancer-associated cachexia markers and key clinical outcomes to ICI therapy – disability-free, hospitalization-free, and overall survival. Consensus weight-based cachexia, WLGS, and NLR measured at the time of ICI initiation are predictive of worse disability-free, hospitalization-free, and overall survival in cancer patients receiving ICI therapy, and may be useful for clinical prognostication and decision-making.

Speaker(s):
Steven Tran
Northwestern University - Feinberg School of Medicine

Author(s):
Steven Tran - Northwestern University - Feinberg School of Medicine; Noah Forrest, BS - Northwestern University - Feinberg School of Medicine; Vijeeth Guggilla, BA - Northwestern University; Geovanni Perottino, MD - Stanford University; Jodi Johnson, PhD - Northwestern University; Jeffrey Sosman, MD - Northwestern University; Ishan Roy, MD, PhD - Northwestern University; Theresa Walunas, PhD - Northwestern University;